Guillermo Del Toro is set to direct a long-planned, often delayed big screen remake of the 1966 sci-fi hit "Fantastic Voyage". James Cameron is behind the plans to bring the remake to reality. The film centers on a group of scientists who are miniaturized and inserted into the body of another prominent scientist in order to remove a blood clot that has endangered his life. Matters of international security depend upon successful completion of the mission but things go awry and endanger the would-be rescuers. The original film, directed by Richard Fleischer, was acclaimed for its (then) state-of-the-art special effects. The film also provided an early career hit for young Raquel Welch who was then a contract player at 20th Century Fox. Other original cast members included Stephen Boyd, Edmond O'Brien and Donald Pleasence. The remake is still in its early stages with no completed script and no casting decided upon.